Drug Information

Drug General Information
Drug ID
D07JXN
Former ID
DIB005399
Drug Name
SPP-600
Synonyms
SPP-630; SPP-635
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Phase 2 [521887]
Company
Speedel Pharma
Target and Pathway
Target(s) Renin, renal Target Info Inhibitor [531738]
KEGG Pathway Renin-angiotensin system
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 521887ClinicalTrials.gov (NCT00376636) Phase IIa Safety and Efficacy Study of SPP635 in Mild to Moderate Hypertension. U.S. National Institutes of Health.
Ref 531738Effect of SPP 635, a renin inhibitor, on intraocular pressure in glaucomatous monkey eyes. Exp Eye Res. 2012 Jan;94(1):146-9.

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