Drug Information
Drug General Information | |||||
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Drug ID |
D08POF
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Former ID |
DCL000036
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Drug Name |
ALX-0081
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Indication | Thrombocytopenia [ICD9: 287.3, 287.4, 287.5; ICD10:D69.6, P61.0] | Phase 2 | [532188] | ||
Company |
Ablynx
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Target and Pathway | |||||
Target(s) | Von Willebrand factor | Target Info | Binder | [550615] | |
Reactome | Platelet degranulation | ||||
Intrinsic Pathway of Fibrin Clot Formation | |||||
Integrin cell surface interactions | |||||
Integrin alphaIIb beta3 signaling | |||||
GRB2:SOS provides linkage to MAPK signaling for Integrins | |||||
p130Cas linkage to MAPK signaling for integrins | |||||
GP1b-IX-V activation signalling | |||||
MAP2K and MAPK activation | |||||
Platelet Adhesion to exposed collagen | |||||
References |
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