Drug General Information
Drug ID	D0L0LR
Former ID	DIB015375
Drug Name	UCL-67022
Synonyms	HDAC inhibitor (multiple myeloma), ST Barts/UCL
Indication	Multiple myeloma [ICD9: 203; ICD10:C90]		Investigative	[543662]
Company	University College London
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1cccc(c1)NC(=O)C(CCCCCC(=O)NO)C(=O)Nc1ccccc1
Target and Pathway
Target(s)	Histone deacetylase 6	Target Info	Inhibitor	[543662]
KEGG Pathway	Alcoholism
	Viral carcinogenesis
Pathway Interaction Database	Signaling events mediated by HDAC Class II
	Signaling events mediated by HDAC Class I
Reactome	NOTCH1 Intracellular Domain Regulates Transcription
	Constitutive Signaling by NOTCH1 PEST Domain Mutants
	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
	Assembly of the primary cilium
WikiPathways	Ectoderm Differentiation
	Neural Crest Differentiation
	Cell Cycle
References
Ref 543662	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2618).
Ref 543662	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2618).

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