Drug General Information
Drug ID	D0TZ4M
Former ID	DIB015295
Drug Name	TRPA1 antagonists
Synonyms	TRPA1 antagonists (pain); TRPA1 antagonists (pain), Johnson & Johnson
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Investigative	[552098]
Company	Johnson & Johnson
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1ccc2c(c1)C(=O)C1=C2NC(=S)N[C@@H]1c1cc(ccc1)OCCCOC
Target and Pathway
Target(s)	Transient receptor potential cation channel subfamily A member 1	Target Info	Antagonist	[543851]
KEGG Pathway	Inflammatory mediator regulation of TRP channels
Reactome	TRP channels
References
Ref 552098	Recent advances in the biology and medicinal chemistry of TRPA1. Future Med Chem. 2010 May;2(5):843-58
Ref 543851	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 485).

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