Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0V8TQ
|
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| Former ID |
DAP000467
|
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| Drug Name |
Aluminium
|
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| Synonyms |
ALUMINUM; Adom; Aluminio; Metana; AO Al; Al alloy; Alaun [German]; Allbri aluminum paste and powder; Alumina fibre; Aluminium bronze; Aluminium flake; Aluminum alloy; Aluminum dehydrated; Aluminum dust; Aluminum metal; Aluminum powder; Aluminum production; Aluminum pyro powders; Aluminum soluble salts; Aluminum welding fumes; Emanay atomized aluminum powder; Metana aluminum paste; Noral Extra Fine Lining Grade; Noral Ink Grade Aluminum; Noral aluminium; Noral aluminum; Noral ink grade aluminium; A 00; A 95; A 99; A 995; A 999; AA 1099; AA1199; AD 1; AD1M; AO A1; AV00; AV000; Aa1193; Aluminum 27; Aluminum A00; Aluminum hydride [UN2463] [Dangerous when wet]; JISC 3108; JISC 3110; L16; NA9260; Pigment metal 1; ALUMINUM, ATOMIZED; Al(0); Aluminium(0); Aluminium, elementar; Aluminum (dust or fume); Aluminum (fume or dust); Aluminum (metal); Aluminum metal, alkyls; Aluminum metal, pyro powders; Aluminum metal, respirable fraction; Aluminum metal, soluble salts; Aluminum metal, total dust; Aluminum metal, welding fumes; Aluminum powder, coated [UN1309] [Flammable solid]; Aluminum powder, uncoated [UN1396] [Dangerous when wet]; Aluminum, elemental; Aluminum, molten [NA9260] [Class 9]; Aluminum, pyro powders; Aluminum, soluble salts; Aluminum, welding fumes; C-Pigment 1; C-Pigment 1 [German]; Noral non-leafing grade; PAP-1; Aluminum, pyro powders/welding fumes; C.I. 77000; ALUMINUM (SEE ALSO ALUMINUM OXIDE 1344-28-1); ALUMINUM, 99.999%; AQUANAL-plus aluminum (Al) 0.02-0.2 mg/L; AQUANAL(R)-plus aluminum (Al) 0.02-0.2 mg/L; 11008_ALDRICH; 11008_RIEDEL; 11009_ALDRICH; 11009_RIEDEL; 11010_ALDRICH; 11010_RIEDEL; 13Al
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| Drug Type |
Small molecular drug
|
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| Indication | Hyperhidrosis [ICD9: 780.8; ICD10:R61] | Approved | [550682] | ||
| Therapeutic Class |
Antiinflammatory Agents
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| Structure |
|
Download2D MOL |
|||
| Formula |
Al
|
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| Canonical SMILES |
[Al]
|
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| InChI |
1S/Al
|
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| InChIKey |
XAGFODPZIPBFFR-UHFFFAOYSA-N
|
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| CAS Number |
CAS 7429-90-5
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
834153, 7422510, 8028403, 10534431, 11653624, 14747261, 15170298, 24434749, 24712323, 24846955, 24846957, 24846959, 24852100, 24852101, 24852849, 24855919, 24856144, 24856145, 24856146, 24856147, 24858790, 24859625, 24859626, 24859627, 24859628, 24859629, 24860574, 24861871, 24863292, 24863322, 24863358, 24867154, 24874032, 24883970, 24895994, 24895995, 24895996, 24895997, 24895998, 24895999, 24896000, 24896170, 24896171, 24896172, 24896173, 24896177, 24896178, 24896179, 24896180, 24896181
|
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| ChEBI ID |
ChEBI:33629
|
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| Target and Pathway | |||||
| Target(s) | Sodium/potassium-transporting ATPase alpha-1 chain | Target Info | Binder | [535839], [536035] | |
| KEGG Pathway | cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | |||||
| Cardiac muscle contraction | |||||
| Adrenergic signaling in cardiomyocytes | |||||
| Insulin secretion | |||||
| Thyroid hormone synthesis | |||||
| Thyroid hormone signaling pathway | |||||
| Aldosterone-regulated sodium reabsorption | |||||
| Endocrine and other factor-regulated calcium reabsorption | |||||
| Proximal tubule bicarbonate reclamation | |||||
| Salivary secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Carbohydrate digestion and absorption | |||||
| Protein digestion and absorption | |||||
| Bile secretion | |||||
| Mineral absorption | |||||
| Reactome | Ion transport by P-type ATPases | ||||
| WikiPathways | Iron uptake and transport | ||||
| References | |||||
| Ref 535839 | The inhibitory effect of aluminium on the (Na+/K+)ATPase activity of rat brain cortex synaptosomes. J Inorg Biochem. 2003 Sep 15;97(1):143-50. | ||||
| Ref 536035 | Effects of aluminium and lead on ATPase activity of knockout +/- mouse cerebral synaptosomes in vitro. Altern Lab Anim. 2004 Oct;32(4):361-7. | ||||
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