Drug Information

Drug General Information
Drug ID
D0F6WW
Former ID
DIB014592
Drug Name
LU-AA33810
Synonyms
LU-AA33810; LU-AE00654; Neuropeptide Y receptor subtype Y5 antagonists (depression); NPY5 antagonists (depression), Lundbeck; Neuropeptide Y receptor subtype Y5 antagonists (depression), Lundbeck
Indication Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10:F32, F33, M32] Investigative [543759]
Company
H Lundbeck A/S
Structure
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2D MOL

3D MOL
Canonical SMILES
O=S(=O)(C)NC[C@H]1CC[C@@H](CC1)Nc1sc2c(n1)c1c(SCC2)cccc<br />1
Target and Pathway
Target(s) Neuropeptide Y receptor 5 Target Info Antagonist [543759]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543759(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 308).
Ref 543759(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 308).

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