Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W4WP
|
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| Former ID |
DIB011295
|
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| Drug Name |
CVT-10216
|
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| Synonyms |
CVT-10083; CVT-10200; CVT-10992; ALDH2 antagonists (alcoholism), CV Therapeutics; ALDH2 antagonists (alcoholism), Gilead Palo Alto; Aldehyde dehydrogenase-2 antagonists (alcoholism), CV Therapeutics
|
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| Drug Type |
Small molecular drug
|
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| Indication | Alcohol use disorders [ICD9: 303; ICD10:F10.2] | Investigative | [543653] | ||
| Company |
Gilead Palo Alto Inc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C24H19NO7S
|
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| Canonical SMILES |
O=S(=O)(Nc1ccc(c2coc3c(c2=O)ccc(c3)OCc2cccc(c2)C(=O)O)c<br />c1)C
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Aldehyde dehydrogenase, mitochondrial | Target Info | Antagonist | [543653] | |
| KEGG Pathway | Glycolysis / Gluconeogenesis | ||||
| Pentose and glucuronate interconversions | |||||
| Ascorbate and aldarate metabolism | |||||
| Fatty acid degradation | |||||
| Valine, leucine and isoleucine degradation | |||||
| Lysine degradation | |||||
| Arginine and proline metabolism | |||||
| Histidine metabolism | |||||
| Tryptophan metabolism | |||||
| beta-Alanine metabolism | |||||
| Glycerolipid metabolism | |||||
| Pyruvate metabolism | |||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| References | |||||
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