Drug Information
Drug General Information | |||||
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Drug ID |
D0L9PA
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Former ID |
DIB014720
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Drug Name |
X-396
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Synonyms |
ALK inhibitors (cancer); X-276; X-353; X-376; X-396; ALK inhibitors (cancer), Xcovery; Anaplastic lymphoma kinase inhibitors (cancer), Xcovery
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Drug Type |
Small molecular drug
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Indication | Advanced solid tumor [ICD9: 140-199; ICD10:C00-C75, C7A, C7B] | Phase 1/2 | [523953] | ||
Company |
Xcovery
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Structure |
Download2D MOL |
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Formula |
C25H25Cl2FN6O3
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Canonical SMILES |
CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=CC(=NN=C2N)C(=O)NC3=CC=C(C=<br />C3)C(=O)N4CCN(CC4)C
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InChI |
1S/C25H25Cl2FN6O3/c1-14(21-17(26)7-8-18(28)22(21)27)37-20-13-19(31-32-23(20)29)24(35)30-16-5-3-15(4-6-16)25(36)34-11-9-33(2)10-12-34/h3-8,13-14H,9-12H2,1-2H3,(H2,29,32)(H,30,35)/t14-/m1/s1
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InChIKey |
ONPGOSVDVDPBCY-CQSZACIVSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | ALK tyrosine kinase receptor | Target Info | Inhibitor | [551778] | |
KEGG Pathway | Non-small cell lung cancer | ||||
WikiPathways | Differentiation Pathway | ||||
References |
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