Drug Information

Drug General Information
Drug ID
D0J9AK
Former ID
DIB007799
Drug Name
MK-944a
Synonyms
L-756423
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Discontinued in Phase 2 [547117]
Company
Merck & Co Inc
Structure
Download
2D MOL

3D MOL
Formula
C39H48N4O5
Canonical SMILES
[C@@H]1(N(C[C@H](C[C@H](C(=O)N[C@H]2c3c(C[C@H]2O)cccc3)<br />Cc2ccccc2)O)CCN(C1)Cc1oc2c(c1)cccc2)C(=O)NC(C)(C)C
PubChem Compound ID
5488192
Target and Pathway
Target(s) HIV protease Target Info Inhibitor [525865]
References
Ref 547117Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013179)
Ref 525865Identification of MK-944a: a second clinical candidate from the hydroxylaminepentanamide isostere series of HIV protease inhibitors. J Med Chem. 2000 Sep 7;43(18):3386-99.

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