Drug General Information
Drug ID
D0SB6K
Former ID
DIB008992
Drug Name
DAT-582
Synonyms
AS-5820
Drug Type
Small molecular drug
Indication Nausea [ICD10:R11] Discontinued in Phase 2 [544822]
Company
Dainippon Pharmaceutical Co Ltd
Structure
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2D MOL

3D MOL

Formula
C22H29Cl2N5O
Canonical SMILES
c1(n[nH]c2c1cccc2)C(=O)N[C@H]1CN(Cc2cc(ccc2)C)CCN(C1)C.<br />Cl.Cl
CAS Number
CAS 141034-42-6
PubChem Compound ID
Target and Pathway
Target(s) 5-Hydroxytryptamine 3 receptor Target Info Antagonist [526818]
References
Ref 544822Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001226)
Ref 5268185-HT3 receptor antagonist effects of DAT-582, (R) enantiomer of AS-5370. Eur J Pharmacol. 1992 Jun 17;216(3):435-40.

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