Drug General Information
Drug ID	D06UFH
Former ID	DIB007578
Drug Name	CZ-112
Indication	Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48]		Terminated	[546939]
Company	Stehlin Foundation For Cancer Research
Structure		Download 2D MOL 3D MOL
Canonical SMILES	n12c(c3c(C2)cc2c([N+](=O)[O-])cccc2n3)cc2c(c1=O)COC(=O)<br />[C@@]2(OC(=O)CC)CC
CAS Number	CAS 194414-80-7
Target and Pathway
Target(s)	Toposisomerase-1	Target Info	Inhibitor	[525971]
NetPath Pathway	IL2 Signaling Pathway
PANTHER Pathway	DNA replication
Pathway Interaction Database	Caspase Cascade in Apoptosis
WikiPathways	Integrated Pancreatic Cancer Pathway
References
Ref 546939	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011353)
Ref 525971	Pharmacology of camptothecin esters. Ann N Y Acad Sci. 2000;922:216-23.

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