Drug General Information
Drug ID
D0IK5F
Former ID
DCL000500
Drug Name
BSI-201
Synonyms
Iniparib; NIBA; INO2BA; IND-71677; SAR-240550; Iniparib, NSC-746045, IND-71677, BSI201, BSI-201; 4-Iodo-3-nitrobenzamide; 4-iodo-3-nitro-benzamide
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 3 [531781], [543086]
Company
Sanofi-Aventis
Structure
Download
2D MOL

3D MOL

Formula
C7H5IN2O3
InChI
InChI=1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11)
InChIKey
MDOJTZQKHMAPBK-UHFFFAOYSA-N
CAS Number
CAS 160003-66-7
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Poly ADP ribose polymerase (PARP) Target Info Modulator [531781]
References
Ref 531781Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro. Clin Cancer Res. 2012 Mar 15;18(6):1655-62.
Ref 543086(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8360).
Ref 531781Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro. Clin Cancer Res. 2012 Mar 15;18(6):1655-62.

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