Drug Information

Drug General Information
Drug ID
D0L2UQ
Former ID
DNCL003496
Drug Name
Pracinostat
Drug Type
Small molecular drug
Indication Myelodysplastic syndrome; Myelofibrosis [ICD9: 238.7, 208.9, 289.83, 709.2; ICD10:D46, C94.4, D47.4] Phase 2 [543091], [548531]
Company
MEI Pharma
Structure
Download
2D MOL

3D MOL
Formula
C20H30N4O2
InChI
InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+
InChIKey
JHDKZFFAIZKUCU-ZRDIBKRKSA-N
PubChem Compound ID
49855250
PubChem Substance ID
104253187, 121142796, 124757307, 125164111, 131480903, 134964553, 135264258, 136340267, 136359913, 136367450, 136920413, 137055167, 137390461, 140705810, 152258538, 160647372, 162011419, 162037638, 162202712, 163668154, 164193974, 172659608, 174520548, 174531534, 185973726, 188899586, 198945398, 202535654, 223366695, 223388553, 223705232, 227106278, 251963214, 252110018, 252160441, 252166577, 252216278, 252451771
Target and Pathway
Target(s) Histone deacetylase Target Info Modulator [543091]
References
Ref 543091(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8365).
Ref 548531Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026393)
Ref 543091(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8365).

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