Drug General Information
Drug ID
D0L1DP
Former ID
DCL000675
Drug Name
ABT-089
Synonyms
Pozanicline; A 94224; ABT 089; Pozanicline (USAN); (R)-2-Methyl-3-(2-pyrrolidinylmethoxy)pyridine; 2-Methyl-3-(2-pyrrolidinylmethoxy)pyridine; 2-Methyl-3-(2S-pyrrolidinylmethoxy)pyridine; 2-methyl-3-[[(2R)-pyrrolidin-2-yl]methoxy]pyridine; 2-methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine
Drug Type
Small molecular drug
Indication Attention deficit hyperactivity disorder; Schizophrenia; Anxiety; Dementia [ICD9: 290-294, 295, 300, 314.0; ICD10:F01-F07, F20, F40-F42, F90] Discontinued in Phase 2 [536499]
Company
Abbott Laboratories
Structure
Download
2D MOL

3D MOL

Formula
C11H16N2O
Canonical SMILES
CC1=C(C=CC=N1)OCC2CCCN2
InChI
1S/C11H16N2O/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10/h3,5-6,10,13H,2,4,7-8H2,1H3/t10-/m0/s1
InChIKey
YRVIKLBSVVNSHF-JTQLQIEISA-N
CAS Number
CAS 161417-03-4
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Nicotinic ACh receptor alpha 4/beta 2 Target Info Modulator
References
Ref 536499Emerging drugs for attention-deficit/hyperactivity disorder. Expert Opin Emerg Drugs. 2007 Sep;12(3):423-34.

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