Drug Information
Drug General Information | |||||
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Drug ID |
D0ZE1O
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Former ID |
DNCL002638
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Drug Name |
Plinabulin
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Synonyms |
NPI-2358
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Drug Type |
Small molecular drug
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Indication | Non-small cell lung cancer [ICD10:C33-C34] | Phase 2 | [549687] | ||
Company |
Nereus Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C19H20N4O2
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Canonical SMILES |
CC(C)(C)C1=C(N=CN1)C=C2C(=O)NC(=CC3=CC=CC=C3)C(=O)N2
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InChI |
1S/C19H20N4O2/c1-19(2,3)16-13(20-11-21-16)10-15-18(25)22-14(17(24)23-15)9-12-7-5-4-6-8-12/h4-11H,1-3H3,(H,20,21)(H,22,25)(H,23,24)/b14-9-,15-10-
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InChIKey |
UNRCMCRRFYFGFX-TYPNBTCFSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
14924620, 24220275, 75782763, 99431571, 99437014, 103751458, 109692962, 124490395, 124757055, 125163859, 131480719, 135263531, 136367349, 136946500, 139161543, 144116282, 152258577, 160647412, 162037484, 162202698, 177748748, 184819679, 188899568, 198973468, 223554899, 223679655, 223701041, 223705266, 226458274, 241382117, 249868020, 251970989, 252063684, 252451819
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Target and Pathway | |||||
Target(s) | Tubulin beta | Target Info | Modulator | ||
PANTHER Pathway | Cytoskeletal regulation by Rho GTPase | ||||
Huntington disease | |||||
References |
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