Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08FDX
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| Former ID |
DNCL002525
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| Drug Name |
MGCD265
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| Drug Type |
Small molecular drug
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| Indication | Non-small cell lung cancer [ICD10:C33-C34] | Phase 2 | [525313] | ||
| Company |
MethylGene
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| Structure |
|
Download2D MOL |
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| Formula |
C26H20FN5O2S2
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| Canonical SMILES |
CN1C=C(N=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(<br />=O)CC5=CC=CC=C5)F
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| InChI |
1S/C26H20FN5O2S2/c1-32-14-20(29-15-32)23-13-19-25(36-23)22(9-10-28-19)34-21-8-7-17(12-18(21)27)30-26(35)31-24(33)11-16-5-3-2-4-6-16/h2-10,12-15H,11H2,1H3,(H2,30,31,33,35)
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| InChIKey |
UFICVEHDQUKCEA-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
53786494, 57467996, 99437110, 103563466, 124757189, 125163993, 125313607, 125329950, 131480853, 136340177, 136367400, 136367877, 144116213, 152043932, 152258291, 160647130, 162011388, 162037559, 162158466, 162202667, 170559183, 174006596, 174531054, 176242979, 177748915, 180386843, 185990454, 188899575, 223592785, 223705039, 229580997, 242060283, 245344485, 249492384, 249820208, 252109880, 252215794
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| Target and Pathway | |||||
| Target(s) | Tyrosine-protein kinase receptor UFO | Target Info | Modulator | ||
| NetPath Pathway | FSH Signaling Pathway | ||||
| Pathway Interaction Database | Validated transcriptional targets of deltaNp63 isoforms | ||||
| Reactome | VEGFA-VEGFR2 Pathway | ||||
| References | |||||
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