Drug Information

Drug General Information
Drug ID
D03IUD
Former ID
DIB013340
Drug Name
Ceftolozane sulfate
Synonyms
Ceftolozane; CXA-101; CXA-301; CXA-301); Cephalosporin derivatives, Astellas; Cephalosporinderivatives, Calixa Therapeutics; FR-193879; FR-264205; FR-295389; CXA-101 (inhaled), Calixa; CXA-101 (inhaled), Cubist; Cephalosporin derivative (H pylori/P aeruginosa infection), Astellas; CXA-101 (inhaled, bacterial lung infection), Cubist
Drug Type
Small molecular drug
Indication Bacterial respiratory tract infection [ICD10:J13, J15] Phase 4 [525160]
Company
Fujisawa Pharmaceutical Co Ltd; Calixa Therapeutics Inc
Structure
Download
2D MOL

3D MOL
Formula
C23H32N12O12S3
Canonical SMILES
CC(C)(O/N=C(\c1nc(sn1)N)/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=<br />O)C(=O)O)C[n+]1cc(c(n1C)N)NC(=O)NCCN)C(=O)O.S(=O)(=O)(O<br />)[O-]
PubChem Compound ID
52918380
Target and Pathway
Target(s) Bacterial penicillin binding protein Target Info Modulator [1572591]
References
Ref 525160ClinicalTrials.gov (NCT02421120) Population Pharmacokinetics and Safety of Intravenous Ceftolozane/Tazobactam in Adult Cystic Fibrosis Patients. U.S. National Institutes of Health.
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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