Drug Information
Drug General Information | |||||
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Drug ID |
D0L9HX
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Former ID |
DCL001037
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Drug Name |
Voclosporin
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Synonyms |
Luveniq; Voclosporin [USAN]; ISA 247; ISA247; ISATX247; LX211; R 1524; ISA-247; ISAtx-247; LX-211; LX-214; R-1524; Trans-ISA 247; Trans-ISA-247; Voclosporin (USAN/INN)
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Drug Type |
Small molecular drug
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Company |
Isotechnika
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Structure |
Download2D MOL |
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Formula |
C63H111N11O12
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Canonical SMILES |
CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C<br />(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC=<br />C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C<br />)C)C)C
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InChI |
1S/C63H111N11O12/c1-25-27-28-29-41(15)53(76)52-57(80)66-44(26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27-28,35-48,50-53,76H,1,26,29-34H2,2-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b28-27+/t41-,42+,43-,44+,45+,46+,47+,48+,50+,51+,52+,53-/m1/s1
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InChIKey |
BICRTLVBTLFLRD-PTWUADNWSA-N
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CAS Number |
CAS 515814-01-4
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
SuperDrug ATC ID |
L04AD03
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Target and Pathway | |||||
Target(s) | Calcineurin | Target Info | Inhibitor | [537117] | |
KEGG Pathway | MAPK signaling pathway | ||||
Calcium signaling pathway | |||||
cGMP-PKG signaling pathway | |||||
Oocyte meiosis | |||||
Apoptosis | |||||
Wnt signaling pathway | |||||
Axon guidance | |||||
VEGF signaling pathway | |||||
Osteoclast differentiation | |||||
Natural killer cell mediated cytotoxicity | |||||
T cell receptor signaling pathway | |||||
B cell receptor signaling pathway | |||||
Long-term potentiation | |||||
Glutamatergic synapse | |||||
Dopaminergic synapse | |||||
Oxytocin signaling pathway | |||||
Glucagon signaling pathway | |||||
Alzheimer's disease | |||||
Amyotrophic lateral sclerosis (ALS) | |||||
Amphetamine addiction | |||||
Tuberculosis | |||||
HTLV-I infection | |||||
WikiPathways | Mitochondrial Gene Expression | ||||
MAPK Signaling Pathway | |||||
G Protein Signaling Pathways | |||||
Cardiac Hypertrophic Response | |||||
Fc epsilon receptor (FCERI) signaling | |||||
Signaling by the B Cell Receptor (BCR) | |||||
T-Cell Receptor and Co-stimulatory Signaling | |||||
Amyotrophic lateral sclerosis (ALS) | |||||
Spinal Cord Injury | |||||
Alzheimers Disease | |||||
miR-targeted genes in muscle cell - TarBase | |||||
miR-targeted genes in lymphocytes - TarBase | |||||
Opioid Signalling | |||||
MicroRNAs in cardiomyocyte hypertrophy | |||||
Physiological and Pathological Hypertrophy of the Heart | |||||
References |
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