Drug General Information
Drug ID	D0I3TU
Former ID	DIB006842
Drug Name	MK-7246
Synonyms	IDDBCP261213; IDDBCP271467
Drug Type	Small molecular drug
Indication	Respiratory disease [ICD10:J00-J99]		Phase 1	[548999]
Company	Merck & Co Inc
Structure		Download 2D MOL 3D MOL
Formula	C21H21FN2O4S
Canonical SMILES	c1ccc2c(c1)n1c(c2CC(=O)O)CC[C@H](C1)N(S(=O)(=O)c1ccc(cc<br />1)F)C
PubChem Compound ID	45268455
Target and Pathway
Target(s)	Putative G-protein coupled receptor 44	Target Info	Modulator	[531277]
Reactome	Prostanoid ligand receptors
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 548999	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031315)
Ref 531277	Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases. Bioorg Med Chem Lett. 2011 Jan 1;21(1):288-93.

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