Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09XIZ
|
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| Former ID |
DNCL002370
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| Drug Name |
JNJ-26481585
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| Drug Type |
Small molecular drug
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| Company |
Janssen Research & Development
|
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| Structure |
|
Download2D MOL |
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| Formula |
C21H26N6O2
|
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| InChI |
InChI=1S/C21H26N6O2/c1-26-14-17(18-4-2-3-5-19(18)26)11-22-10-15-6-8-27(9-7-15)21-23-12-16(13-24-21)20(28)25-29/h2-5,12-15,22,29H,6-11H2,1H3,(H,25,28)
|
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| InChIKey |
PAWIYAYFNXQGAP-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
16640562, 23662539, 42656475, 80686572, 99437202, 124756995, 125163800, 134964409, 136340274, 136367295, 137574407, 144116093, 152344185, 160687244, 160830062, 162037431, 162108664, 162202708, 163094379, 163312351, 163394407, 163842923, 164193969, 172919123, 174006335, 177748745, 185992949, 187051805, 188899585, 198951338, 202535632, 204363605, 223601329, 223705149, 228477766, 245359853, 249867668, 250212580, 252070148, 252215623, 252440486
|
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| Target and Pathway | |||||
| Target(s) | Histone deacetylase | Target Info | Modulator | [542523] | |
| References | |||||
| Ref 530481 | JNJ-26481585, a novel "second-generation" oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity. Clin Cancer Res. 2009 Nov 15;15(22):6841-51. | ||||
| Ref 542523 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7503). | ||||
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