Drug Information
Drug General Information | |||||
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Drug ID |
D0D1BR
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Former ID |
DNCL002989
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Drug Name |
GS-7340
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Synonyms |
NtRTI
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Drug Type |
Small molecular drug
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Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Phase 2 | [523854] | ||
Company |
Gilead Sciences
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Structure |
Download2D MOL |
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Formula |
C21H29N6O5P
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Canonical SMILES |
CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C1N=CN=C2N)OC3=CC=<br />CC=C3
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InChI |
1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15-,16+,33-/m1/s1
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InChIKey |
LDEKQSIMHVQZJK-GNGHXOLXSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | HIV reverse transcriptase | Target Info | Inhibitor | [527526] | |
References | |||||
Ref 523854 | ClinicalTrials.gov (NCT01565850) Safety and Efficacy of Darunavir/Cobicistat/Emtricitabine/GS-7340 Single Tablet Regimen Versus Cobicistat-boosted Darunavir Plus Emtricitabine/Tenofovir Disoproxil Fumarate Fixed Dose Combination in HIV-1 Infected, Antiretroviral Treatment Naive Adults. U.S. National Institutes of Health. |
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