Drug Information

Drug General Information
Drug ID
D04FKX
Former ID
DNCL002410
Drug Name
D-3263
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 1 [522576]
Company
Dendreon
Structure
Download
2D MOL

3D MOL
Formula
C12H16BF4N5O2
Canonical SMILES
[B-](F)(F)(F)F.CN(C)C(=[N+](C)C)ON1C(=O)C2=CC=CC=C2N=N1
InChI
1S/C12H16N5O2.BF4/c1-15(2)12(16(3)4)19-17-11(18)9-7-5-6-8-10(9)13-14-17;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1
InChIKey
FOBCPCIJLQTYBT-UHFFFAOYSA-N
PubChem Compound ID
10882602
PubChem Substance ID
15928782, 23130537, 24863207, 42062750, 57375470, 57649719, 75924159, 87245350, 91694285, 117656930, 118318595, 125339590, 126652203, 126664142, 136990598, 143491797, 152049580, 152243761, 160870982, 162186783, 162246152, 162278347, 163303114, 163782493, 163802232, 174526928, 184581691, 204362693, 223391286, 223656931, 223812404, 226840397, 252150885, 252265924, 252355404, 252430570, 252810060
Target and Pathway
Target(s) TRPM8 protein Target Info Modulator [544089]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 522576ClinicalTrials.gov (NCT00839631) Dose Escalation Study of EC D-3263 HCl in Advanced Solid Tumors. U.S. National Institutes of Health.
Ref 544089Best of the 2009 AUA Annual Meeting: Highlights from the 2009 Annual Meeting of the American Urological Association, April 25-30, 2009, Chicago, IL. Rev Urol. 2009 Spring; 11(2): 82-107.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.