Drug Information

Drug General Information
Drug ID
D0E3NZ
Former ID
DIB001377
Drug Name
L-696229
Synonyms
3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridine-2(1H)-one
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Discontinued in Phase 2 [544904]
Structure
Download
2D MOL

3D MOL
Formula
C17H18N2O2
Canonical SMILES
CCC1=C(NC(=O)C(=C1)CCC2=NC3=CC=CC=C3O2)C
InChI
1S/C17H18N2O2/c1-3-12-10-13(17(20)18-11(12)2)8-9-16-19-14-6-4-5-7-15(14)21-16/h4-7,10H,3,8-9H2,1-2H3,(H,18,20)
InChIKey
MHUVLRNBDLFMHQ-UHFFFAOYSA-N
CAS Number
CAS 135525-71-2
PubChem Compound ID
72352
PubChem Substance ID
599038, 8032025, 8195150, 14750966, 43128528, 57318673, 79419887, 103122197, 103290927, 104352723, 117584476, 125690317, 128597791, 135029538, 162389149, 163306048, 163356163, 224955253, 231387172
Target and Pathway
Target(s) HIV reverse transcriptase Target Info Inhibitor [544027], [551871]
References
Ref 544904Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001460)
Ref 544027L-696,229 specifically inhibits human immunodeficiency virus type 1 reverse transcriptase and possesses antiviral activity in vitro.. Antimicrob Agents Chemother. 1992 May; 36(5): 1019-1023.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.