Drug Information

Drug General Information
Drug ID
D04MYC
Former ID
DIB012374
Drug Name
NSC-625487
Synonyms
1-(2,6-Difluorophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Investigative [525585], [551871]
Structure
Download
2D MOL

3D MOL
Formula
C15H10F2N2S
Canonical SMILES
C1C2=NC3=CC=CC=C3N2C(S1)C4=C(C=CC=C4F)F
InChI
1S/C15H10F2N2S/c16-9-4-3-5-10(17)14(9)15-19-12-7-2-1-6-11(12)18-13(19)8-20-15/h1-7,15H,8H2
InChIKey
AMLBAOPYPUXEQF-UHFFFAOYSA-N
CAS Number
CAS 138226-12-7
PubChem Compound ID
122665
PubChem Substance ID
492426, 516755, 516756, 600620, 6409764, 8137490, 10240174, 11412277, 14849046, 29303010, 46510874, 57340146, 79886371, 103236503, 104416394, 127427968, 135078579, 142603309, 229225821, 241033800
Target and Pathway
Target(s) HIV reverse transcriptase Target Info Inhibitor [525585], [551871]
References
Ref 525585Synthesis and biological activity of novel 1H,3H-thiazolo[3,4-a]benzimidazoles: non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors. Antivir Chem Chemother. 1999 Jul;10(4):211-7.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 525585Synthesis and biological activity of novel 1H,3H-thiazolo[3,4-a]benzimidazoles: non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors. Antivir Chem Chemother. 1999 Jul;10(4):211-7.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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