Drug Information

Drug General Information
Drug ID
D08ZAX
Former ID
DIB003516
Drug Name
RS-93522
Synonyms
2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid methyl 2-[4-(2,3-dihydroxypropoxy)phenyl]ethyl diester; 2-[4-(2,3-Dihydroxypropoxy)phenyl]ethyl 2,6-dimethyl-3-(methoxycarbonyl)-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Terminated [545315]
Structure
Download
2D MOL

3D MOL
Formula
C27H30N2O9
Canonical SMILES
CC1=C(C(C(=C(N1)C)C(=O)OCCC2=CC=C(C=C2)OCC(CO)O)C3=CC(=<br />CC=C3)[N+](=O)[O-])C(=O)OC
InChI
1S/C27H30N2O9/c1-16-23(26(32)36-3)25(19-5-4-6-20(13-19)29(34)35)24(17(2)28-16)27(33)37-12-11-18-7-9-22(10-8-18)38-15-21(31)14-30/h4-10,13,21,25,28,30-31H,11-12,14-15H2,1-3H3
InChIKey
QLNAYPDWIWUVHP-UHFFFAOYSA-N
CAS Number
CAS 104060-12-0
PubChem Compound ID
128487
PubChem Substance ID
10242056, 14962382, 29307527, 57342595, 76833317, 104368241, 126436395, 135084497, 162356803, 162770968, 224872336, 232906923
Target and Pathway
Target(s) Calcium channel Target Info Blocker [530703], [551871]
References
Ref 545315Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002793)
Ref 530703Intranasal delivery of RS-93522, a dihydropyridine-type calcium-channel antagonist. Pharm Res. 1991 Jan;8(1):134-5.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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