Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08EEU
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| Former ID |
DIB016258
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| Drug Name |
Englitazone sodium
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| Synonyms |
Englitazone sodium < Rec INNM; CP-68722 (racemate); CP-72467-02; CP-72467-2; (-)-5-[2(R)-Benzyl-3,4-dihydro-2H-benzopyran-6-ylmethyl]thiazolidine-2,4-dione sodium salt
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| Drug Type |
Small molecular drug
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| Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Phase 1 | [526541] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C20H18NNaO3S
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| Canonical SMILES |
O=C1NC(=O)C(Cc2ccc3OC(Cc4ccccc4)CCc3c2)S1
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| InChI |
1S/C20H19NO3S/c22-19-18(25-20(23)21-19)12-14-6-9-17-15(10-14)7-8-16(24-17)11-13-4-2-1-3-5-13/h1-6,9-10,16,18H,7-8,11-12H2,(H,21,22,23)
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| InChIKey |
MVDXXGIBARMXSA-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Peroxisome proliferator activated receptor gamma | Target Info | Agonist | [526541], [551871] | |
| PANTHER Pathway | CCKR signaling map ST | ||||
| WikiPathways | Wnt Signaling Pathway Netpath | ||||
| Nuclear Receptors in Lipid Metabolism and Toxicity | |||||
| Differentiation of white and brown adipocyte | |||||
| Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |||||
| Transcriptional Regulation of White Adipocyte Differentiation | |||||
| Adipogenesis | |||||
| SREBP signalling | |||||
| Nuclear Receptors | |||||
| References | |||||
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