Drug Information

Drug General Information
Drug ID
D0TF1E
Former ID
DIB009805
Drug Name
A-366833
Synonyms
5-[(1R,5S)-3,6-Diazabicyclo[3.2.0]hept-6-yl]pyridine-3-carbonitrile
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Preclinical [547885]
Structure
Download
2D MOL

3D MOL
Formula
C11H12N4
Canonical SMILES
C1C2CN(C2CN1)C3=CN=CC(=C3)C#N
InChI
1S/C11H12N4/c12-2-8-1-10(5-13-3-8)15-7-9-4-14-6-11(9)15/h1,3,5,9,11,14H,4,6-7H2/t9-,11-/m1/s1
InChIKey
GPXAWLDGWSBLKM-MWLCHTKSSA-N
CAS Number
CAS 370882-41-0
PubChem Compound ID
9942427
PubChem Substance ID
14916557, 24214176, 76209564, 103542239, 104096071, 162503946, 163642288, 198961224, 226948527, 246004568
Target and Pathway
Target(s) Nicotinic ACh receptor alpha 4/beta 2 Target Info Modulator [531558]
References
Ref 547885Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020139)
Ref 531558Antinociceptive activity of alpha4beta2* neuronal nicotinic receptor agonist A-366833 in experimental models of neuropathic and inflammatory pain. Eur J Pharmacol. 2011 Oct 1;668(1-2):155-62.

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