Drug General Information
Drug ID
D00RFZ
Former ID
DIB004335
Drug Name
PSI-6130
Synonyms
R-1656; RO-4995855; Hepatitis C virus therapy, Pharmasset/Roche; PSI-6130-DP; PSI-6130-MP; PSI-6130-TP
Drug Type
Small molecular drug
Indication HCV infection [ICD9: 070.4, 070.5, 070.70; ICD10:B17.1, B18.2] Terminated [548353]
Company
Pharmasset Inc
Structure
Download
2D MOL

3D MOL

Formula
C10H14FN3O4
Canonical SMILES
[C@]1([C@H](n2c(=O)nc(cc2)N)O[C@@H]([C@H]1O)CO)(F)C
CAS Number
CAS 817204-33-4
PubChem Compound ID
Target and Pathway
Target(s) Hepatitis C virus NS5B polymerase Target Info Inhibitor [530284]
References
Ref 548353Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024904)
Ref 530284An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase. J Org Chem. 2009 Sep 4;74(17):6819-24.

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