TTD | Drug: D04ZWQ

Drug General Information
Drug ID	D04ZWQ
Former ID	DIB007011
Drug Name	Org-25435
Drug Type	Small molecular drug
Indication	Epilepsy [ICD10:G40]		Phase 1	[522942]
Company	Organon BioSciences
Structure		Download 2D MOL 3D MOL
Formula	C19H31NO6
Canonical SMILES	c1(OC(=O)[C@H](N(CCOC)CCOC)CC)c(cc(cc1OC)C)OC
PubChem Compound ID	11036024
Target and Pathway
Target(s)	GABA A receptor	Target Info	Modulator	[530997]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 522942	ClinicalTrials.gov (NCT01062867) First Administration to Man Of Org 25435 a New Intravenous Anesthetic. U.S. National Institutes of Health.
Ref 530997	First administration to man of Org 25435, an intravenous anaesthetic: A Phase 1 Clinical Trial. BMC Anesthesiol. 2010 Jun 29;10:10.

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Drug Information