Drug General Information
Drug ID
D0Y8IF
Former ID
DIB014830
Drug Name
MX-781
Indication Breast cancer [ICD9: 174, 175; ICD10:C50] Terminated [546931]
Company
Maxia Pharmaceuticals Inc
Structure
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2D MOL

3D MOL

Canonical SMILES
C12(c3cc(C(=O)/C=C/c4ccc(C(=O)O)cc4)ccc3OCOCCOC)CC3CC(C<br />1)CC(C2)C3
CAS Number
CAS 217949-67-2
Target and Pathway
Target(s) Retinoic acid receptor Target Info Modulator [527172]
References
Ref 546931Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011240)
Ref 527172The retinoid antagonist MX781 induces clusterin expression in prostate cancer cells via heat shock factor-1 and activator protein-1 transcription factors. Cancer Res. 2004 Aug 15;64(16):5905-12.

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