Drug Information

Drug General Information
Drug ID
D0Y3XA
Former ID
DNC003168
Drug Name
Ge2270a
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Phase 1 [544022]
Structure
Download
2D MOL

3D MOL
Formula
C56H55N15O10S6
Canonical SMILES
CC1=C2C(=O)NC(C3=NC(=C(S3)COC)C(=O)NCC(=O)NC(C4=NC(=CS4<br />)C5=NC(=CS5)C6=C(C=CC(=N6)C7=NC(=CS7)C8=NC(CO8)C(=O)N9C<br/>CCC9C(=O)N)C3=NC(=CS3)C(=O)NC(C(=N2)S1)CC(=O)NC)C(C1=CC<br />=CC=C1)O)C(C)C
InChI
1S/C56H55N15O10S6/c1-24(2)39-55-70-42(36(87-55)19-80-5)47(77)59-17-38(73)67-43(44(74)26-10-7-6-8-11-26)54-66-34(23-85-54)52-63-31(20-83-52)41-27(50-64-32(21-82-50)46(76)61-29(16-37(72)58-4)53-69-40(25(3)86-53)48(78)68-39)13-14-28(60-41)51-65-33(22-84-51)49-62-30(18-81-49)56(79)71-15-9-12-35(71)45(57)75/h6-8,10-11,13-14,20-24,29-30,35,39,43-44,74H,9,12,15-19H2,1-5H3,(H2,57,75)(H,58,72)(H,59,77)(H,61,76)(H,67,73)(H,68,78)
InChIKey
JMDULECOHIXMNX-UHFFFAOYSA-N
CAS Number
CAS 2007-07-0
PubChem Compound ID
16129640
PubChem Substance ID
14221, 5006400, 14841927, 28730008, 40663445, 50070479, 50071120, 57379894, 135229365, 141313976, 237581924, 249013122
Target and Pathway
Target(s) Elongation factor 1-alpha Target Info Inhibitor [551393]
Elongation factor 1-alpha 1 Target Info Inhibitor [551393]
References
Ref 544022In vitro antimicrobial activity of a new antibiotic, MDL 62,879 (GE2270 A).. Antimicrob Agents Chemother. 1993 April; 37(4): 741-745.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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