Drug General Information
Drug ID	D04PGO
Former ID	DIB005787
Drug Name	MDL-28133A
Drug Type	Small molecular drug
Indication	Thromboembolism [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82]		Terminated	[545319]
Company	Hoechst Marion Roussel Inc
Structure		Download 2D MOL 3D MOL
Formula	C21H24ClFN2O4S
Canonical SMILES	S(=O)(=O)(Nc1ccc(C(=O)C2CCN(CC(=O)c3ccc(cc3)F)CC2)cc1)C<br />.Cl
CAS Number	CAS 136861-96-6
PubChem Compound ID	132001
Target and Pathway
Target(s)	5-HT 2 receptor	Target Info	Modulator	[533621]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
References
Ref 545319	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002814)
Ref 533621	Effects of MDL 28,133A, a 5-HT2 receptor antagonist, on platelet aggregation and coronary thrombosis in dogs. J Cardiovasc Pharmacol. 1994 Nov;24(5):761-72.

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