Drug General Information
Drug ID	D0YP0C
Former ID	DIB009081
Drug Name	DT-TX-30
Synonyms	DT-TX-30-SE
Indication	Angina pectoris [ICD9: 413; ICD10:I20]		Phase 1	[534431]
Company	Boehringer Ingelheim Corp
Structure		Download 2D MOL 3D MOL
Canonical SMILES	S(=O)(=O)(c1ccc(cc1)Cl)NCCc1ccc(/C(=C\CCCC(=O)O)/c2cncc<br />c2)cc1
CAS Number	CAS 127369-68-0
Target and Pathway
Target(s)	Thromboxane A2 receptor	Target Info	Antagonist	[534431]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	Prostanoid ligand receptors
	G alpha (q) signalling events
	G alpha (12/13) signalling events
	Thromboxane signalling through TP receptor
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 534431	DTTX30, a combined thromboxane receptor antagonist and thromboxane synthetase inhibitor, prevents coronary thrombosis in anesthetized dogs. Basic Res Cardiol. 1997 Jun;92(3):181-90.
Ref 534431	DTTX30, a combined thromboxane receptor antagonist and thromboxane synthetase inhibitor, prevents coronary thrombosis in anesthetized dogs. Basic Res Cardiol. 1997 Jun;92(3):181-90.

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