Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08QHS
|
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| Former ID |
DCL000105
|
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| Drug Name |
DG041
|
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| Synonyms |
DTSI; D-000151746; DG-041
|
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| Drug Type |
Small molecular drug
|
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| Company |
DeCODE genetics
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| Structure |
|
Download2D MOL |
|||
| Formula |
C23H15Cl4FN2O3S2
|
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| InChI |
InChI=1S/C23H15Cl4FN2O3S2/c1-12-10-30(11-14-2-4-15(24)7-18(14)25)22-13(6-16(28)8-17(12)22)3-5-20(31)29-35(32,33)21-9-19(26)23(27)34-21/h2-10H,11H2,1H3,(H,29,31)/b5-3+
|
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| InChIKey |
BFBTVZNKWXWKNZ-HWKANZROSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Prostaglandin E2 receptor EP3 subtype | Target Info | Antagonist | [536080], [536517] | |
| NetPath Pathway | IL2 Signaling Pathway | ||||
| References | |||||
| Ref 541141 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5822). | ||||
| Ref 547397 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015910) | ||||
| Ref 536080 | Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial. JAMA. 2005 May 11;293(18):2245-56. | ||||
| Ref 536517 | BAY x 1005 attenuates atherosclerosis in apoE/LDLR - double knockout mice. J Physiol Pharmacol. 2007 Sep;58(3):583-8. | ||||
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