Drug General Information
Drug ID	D0V4GT
Former ID	DIB001203
Drug Name	CMI-206
Synonyms	IDDB8444
Indication	Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25]		Terminated	[551572]
Company	CytoMed Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C(=O)(Nc1c(c(cc([C@H]2O[C@H](c3cc(c(c(c3)OC)OC)OC)CC2)c<br />1)OC)OCCC)N(O)CCCC
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Modulator
	Platelet-activating factor receptor	Target Info	Modulator
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosishsa04020:Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Staphylococcus aureus infection
NetPath Pathway	IL4 Signaling PathwayNetPath_17:IL5 Signaling Pathway
	Leptin Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (q) signalling events
	Interferon gamma signaling
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient NetworkWP455:GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Interferon gamma signaling
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 551572	Cmi206: A potent dual platelet activating factor antagonist and 5-lipoxygenase inhibitor. Bioorganic & Medicinal Chemistry Letters. 03/1995; 5(6):643-648.

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