Drug Information
Drug General Information | |||||
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Drug ID |
D0MW3H
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Former ID |
DNC003574
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Drug Name |
CIPEMASTAT
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C22H36N4O5
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InChI |
InChI=1S/C22H36N4O5/c1-22(2)20(29)26(21(30)24(22)3)14-17(18(27)23-31)16(13-15-9-5-6-10-15)19(28)25-11-7-4-8-12-25/h15-17,31H,4-14H2,1-3H3,(H,23,27)/t16-,17+/m1/s1
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InChIKey |
GFUITADOEPNRML-SJORKVTESA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Neutrophil collagenase | Target Info | Modulator | [532656] | |
Interstitial collagenase | Target Info | Modulator | [532656] | ||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix MetalloproteinasesR-HSA-1442490:Collagen degradation | |||||
Activation of Matrix Metalloproteinases | |||||
Basigin interactions | |||||
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | |||||
WikiPathways | Activation of Matrix Metalloproteinases | ||||
Matrix MetalloproteinasesWP366:TGF beta Signaling Pathway | |||||
Bladder Cancer | |||||
Degradation of collagen | |||||
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
Oncostatin M Signaling Pathway | |||||
Prostate Cancer | |||||
Integrated Breast Cancer Pathway | |||||
Integrated Cancer pathway | |||||
Cell surface interactions at the vascular wall | |||||
Matrix Metalloproteinases | |||||
References | |||||
Ref 532656 | Matrix metalloproteinase inhibition lowers mortality and brain injury in experimental pneumococcal meningitis. Infect Immun. 2014 Apr;82(4):1710-8. | ||||
Ref 541601 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6466). |
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