Drug General Information
Drug ID	D06HYG
Former ID	DIB010897
Drug Name	Barucainide
Drug Type	Small molecular drug
Indication	Heart arrhythmia [ICD10:I47-I49]		Terminated	[544576]
Company	BASF AG
Structure		Download 2D MOL 3D MOL
Formula	C22H30N2O2
Canonical SMILES	c12c(c(nc(c1OCCCCNC(C)C)C)Cc1ccccc1)COC2
CAS Number	CAS 79784-22-8
PubChem Compound ID	146795
Target and Pathway
Target(s)	E3 ubiquitin protein ligase COP1	Target Info	Modulator	[532190]
KEGG Pathway	p53 signaling pathway
	Ubiquitin mediated proteolysis
PANTHER Pathway	P53 pathway feedback loops 1
Pathway Interaction Database	ATM pathway
	Direct p53 effectors
	p53 pathway
References
Ref 544576	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000197)
Ref 532190	Barucainide, a novel class Ib antiarrhythmic agent with a slow kinetic property: electrophysiologic observations in isolated canine and rabbit cardiac muscle. Am Heart J. 1990 May;119(5):1050-60.

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