Drug General Information
Drug ID
D01FUL
Former ID
DIB012145
Drug Name
Balapiravir
Synonyms
Balapiravir hydrochloride; HCV NS5B polymerase inhibitor, Roche; R-1626; RO4588161-001; RNA polymerase inhibitor (HCV infection), Roche; RNA polymerase inhibitor (hepatitis C infection), Roche; R-1479 prodrug (HCV infection), Roche
Drug Type
Small molecular drug
Indication HCV infection [ICD9: 070.4, 070.5, 070.70; ICD10:B17.1, B18.2] Phase 1 [522994]
Company
Roche
Structure
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2D MOL

3D MOL

Formula
C21H30N6O8
Canonical SMILES
[C@@H]1([C@H]([C@@H](O[C@]1(N=[N+]=[N-])COC(=O)C(C)C)n1<br />c(=O)nc(cc1)N)OC(=O)C(C)C)OC(=O)C(C)C
CAS Number
CAS 690270-29-2
PubChem Compound ID
Target and Pathway
Target(s) Hepatitis C virus NS5B polymerase Target Info Inhibitor [529730]
References
Ref 522994ClinicalTrials.gov (NCT01096576) A Study of Balapiravir in Patients With Dengue Virus Infection. U.S. National Institutes of Health.
Ref 529730R-1626, a specific oral NS5B polymerase inhibitor of hepatitis C virus. IDrugs. 2008 Oct;11(10):738-49.

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