Drug Information
Drug General Information | |||||
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Drug ID |
D07GIB
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Former ID |
DCL000470
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Drug Name |
AZD5672
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Drug Type |
Small molecular drug
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Company |
AstraZeneca
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Structure |
Download2D MOL |
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Formula |
C31H43F2N3O5S2
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InChI |
InChI=1S/C31H43F2N3O5S2/c1-4-36(31(37)19-23-5-7-29(8-6-23)42(2,38)39)28-11-14-34(15-12-28)16-13-30(25-20-26(32)22-27(33)21-25)24-9-17-35(18-10-24)43(3,40)41/h5-8,20-22,24,28,30H,4,9-19H2,1-3H3/t30-/m1/s1
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InChIKey |
QOSMEMHKXNNIGG-SSEXGKCCSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | C-C chemokinereceptor type 5 | Target Info | Antagonist | [550288] | |
Pathway Interaction Database | IL12-mediated signaling events | ||||
References | |||||
Ref 531058 | Preclinical and clinical investigation of a CCR5 antagonist, AZD5672, in patients with rheumatoid arthritis receiving methotrexate. Arthritis Rheum. 2010 Nov;62(11):3154-60. | ||||
Ref 542666 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7686). |
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