Drug Information

Drug General Information
Drug ID
D0H6TP
Former ID
DAP000830
Drug Name
Monobenzone
Synonyms
Agerite; Alba; Benoquin; Benzoquin; Carmifal; Depigman; Dermochinona; Leucodinine; Monobenzon; Monobenzona; Monobenzonum; PBP; Pigmex; Superlite; Agerite alba; Benzyl hydroquinone; Hydrochinon monobenzylether; Hydrochinon monobenzylether [Czech]; Hydroquinone benzyl ether; Hydroquinone monobenzyl ether; ICN brand of monobenzone; Monobenzone [INN]; Monobenzyl Ether of Hydroquinone; Monobenzyl ether hydroquinone; Monobenzyl hydroquinone; Alba-Dome; Benoquin (TN); Benoquin, Monobenzone; Benzyl p-hydroxyphenyl ether; Carmifal(TN); Depigman (TN); Dermochinona (TN); HYDROQUINONE MONOBENZYL ETHER, N F; Leucodinine (TN); Monobenzon (TN); Monobenzona [INN-Spanish]; Monobenzonum [INN-Latin]; Novo-depigman; P-BENZYLOXYPHENOL; P-Hydroxyphenyl benzyl ether; Pigmex (TN); Superlite (TN); Superlite (antioxidant); Monobenzone (USP/INN); P-(BENZYLOXY)PHENOL; 4-(Benzyl-Oxy)Phenol; 4-(Benzyloxy)phenol; 4-(Benzyloxyl)phenol; 4-(Phenylmethoxy)phenol; 4-Benzyloxyphenol; 4-benzyloxy phenol; 4-phenylmethoxy-phenol; 4-phenylmethoxyphenol
Drug Type
Small molecular drug
Indication Vitiligo [ICD9: 709.01; ICD10:L80] Approved [538404], [541911]
Therapeutic Class
Dermatologic Agents
Structure
Download
2D MOL

3D MOL
Formula
C13H12O2
InChI
InChI=1S/C13H12O2/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-9,14H,10H2
InChIKey
VYQNWZOUAUKGHI-UHFFFAOYSA-N
CAS Number
CAS 103-16-2
PubChem Compound ID
7638
PubChem Substance ID
68818, 91829, 6305368, 7847054, 8155204, 10502657, 10561358, 11112252, 11466940, 11468060, 11486709, 12016119, 15114599, 24849729, 29226461, 46507466, 47206799, 47291387, 47440557, 47662549, 47960021, 48185249, 48413876, 48422013, 49699206, 49829901, 49857419, 50100397, 50415393, 51072586, 53787760, 56368754, 57324378, 85171308, 87564047, 92125750, 92166547, 92714762, 93165455, 93616918, 99216657, 99343594, 103469378, 103810887, 103914634, 104253287, 104315544, 104667978, 117535182, 117615110
SuperDrug ATC ID
D11AX13
SuperDrug CAS ID
cas=000103162
Target and Pathway
Target(s) Tyrosine oxidase Target Info Inhibitor [537026]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 538404FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 008173.
Ref 541911(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6830).
Ref 537026Identification of an Alkylhydroquinone from Rhus succedanea as an Inhibitor of Tyrosinase and Melanogenesis. J Agric Food Chem. 2009 Mar 25;57(6):2200-5.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.