Drug Information

Drug General Information
Drug ID
D07OIX
Former ID
DAP001226
Drug Name
Iodipamide
Synonyms
Adipiodon; Adipiodona; Adipiodone; Adipiodonum; Bilignost; Bilignostum; Biligrafin; Cholografin; Cholospect; IDB; Transbilix; Iodipamic acid; Iodipamide [USAN]; Adipiodona [INN-Spanish]; Adipiodonum [INN-Latin]; Iodipamide (USP); Adipiodone (JAN/INN); N,N''-Adipoyl-bis(3-amino-2,4,6-triiodbenzoesaeure); 3,3'(Adipoyldiimino)bis(2,4,6-triiodobenzoic acid); 3,3'-(Adipoyldiimino)bis(2,4,6-triiodobenzoic acid); 3,3'-Adipoyldiiminobis(2,4,6-triiodobenzoic Acid); 3,3'-[(1,6-DIOXOHEXANE-1,6-DIYL)DIIMINO]BIS(2,4,6-TRIIODOBENZOIC ACID); 3-[5-[(3-CARBOXY-2,4,6-TRIIODO-PHENYL)CARBAMOYL]PENTANOYLAMINO]-2,4,6-TRIIODO-BENZOIC ACID; 3-[[6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
Drug Type
Small molecular drug
Indication Cholecystography; Gallbladder disease [ICD9: 574, 575; ICD10:K81, K82, K80-K82] Approved [538417], [542423], [551871]
Therapeutic Class
Contrast Media
Structure
Download
2D MOL

3D MOL
Formula
C20H14I6N2O6
InChI
InChI=1S/C20H14I6N2O6/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34)
InChIKey
FFINMCNLQNTKLU-UHFFFAOYSA-N
CAS Number
CAS 606-17-7
PubChem Compound ID
3739
PubChem Substance ID
5243536, 7848837, 7888314, 8027952, 8152362, 11112428, 11466967, 11468087, 11486783, 15040584, 24895909, 29222859, 46507320, 47193872, 47291269, 47291270, 47365354, 48334649, 48416112, 49699217, 49885500, 50100437, 57321966, 57654289, 79570445, 85787388, 87571658, 92125844, 103125333, 103764971, 103914611, 104304379, 117573138, 118307490, 121363515, 124800039, 124882364, 125537198, 134338465, 134359921, 134977667, 137006031, 143432639, 143831592, 144107630, 144207053, 152104311, 160967695, 162880254, 164811140
SuperDrug ATC ID
V08AC04
SuperDrug CAS ID
cas=000606177
Target and Pathway
Target(s) Serum albumin Target Info Binder [536697]
Pathway Interaction Database FOXA2 and FOXA3 transcription factor networks
Reactome Platelet degranulation
Recycling of bile acids and salts
HDL-mediated lipid transport
Scavenging of heme from plasma
WikiPathways Human Complement System
Binding and Uptake of Ligands by Scavenger Receptors
Lipid digestion, mobilization, and transport
Transport of vitamins, nucleosides, and related molecules
Bile acid and bile salt metabolism
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 538417FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 009321.
Ref 542423(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7400).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536697Determining binding sites of drugs on human serum albumin using FIA-QCM. Biosens Bioelectron. 2008 Sep 15;24(1):48-54. Epub 2008 Mar 21.

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