Drug Information

Drug General Information
Drug ID
D0W9LX
Former ID
DAP000135
Drug Name
Carvedilol
Synonyms
Artist; Carvedilolum; Coreg; Coropres; Coropress; Dibloc; Dilatrend; Eucardic; Kredex; Querto; Atlana Pharma brand of carvedilol; Carvedilolum [Latin]; Coreg CR; GlaxoSmithKline brand of carvedilol; Lakeside brand of carvedilol; Roche brand of carvedilol; BM 14190; DQ 2466; SKF 105517; Artist (TN); BM-14190; Carloc (TN); Coreg (TN); DQ-2466; Dilatrend (TN); EG-P042; Eucardic (TN); BM-14-190; BM-14.190; Carvedilol, 14C-labeled; SK&F-105517; Carvedilol (JAN/USAN/INN); Carvedilol [USAN:INN:BAN:JAN]; Carvedilol, (R)-isomer; Carvedilol, (S)-isomer; Carvedilol, (+-)-isomer; (+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol; (+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol; (+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol; 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol; 1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol; 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol; 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
Drug Type
Small molecular drug
Indication Congestive heart failure [ICD9: 428; ICD10:I50] Approved [536361], [540906]
Therapeutic Class
Vasodilator Agents
Company
GlaxoSmithKline plc
Structure
Download
2D MOL

3D MOL
Formula
C24H26N2O4
InChI
InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
InChIKey
OGHNVEJMJSYVRP-UHFFFAOYSA-N
CAS Number
CAS 72956-09-3
PubChem Compound ID
2585
PubChem Substance ID
9092, 7387304, 7847321, 7978866, 8151709, 11364559, 11367121, 11369683, 11372422, 11374391, 11377845, 11485621, 11489489, 11490997, 11492451, 11495479, 11528712, 12013067, 14855122, 26719722, 26719723, 29221745, 46386749, 46386871, 46505146, 47805057, 48415707, 49681735, 49834917, 50112972, 50112973, 53789407, 56313592, 56413047, 56464135, 57321386, 76450239, 81040900, 81092790, 85209910, 85789499, 85789708, 87560280, 90341342, 92251378, 92307922, 92308493, 92308705, 92711411, 103197484
ChEBI ID
ChEBI:3441
SuperDrug ATC ID
C07AG02
SuperDrug CAS ID
cas=072956093
Target and Pathway
Target(s) Alpha-1 adrenergic receptor Target Info Antagonist [537409]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 540906(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 551).
Ref 537409Beta-blockers in the treatment of hypertension: are there clinically relevant differences? Postgrad Med. 2009 May;121(3):90-8.

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