Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00OTT
|
||||
| Former ID |
DNC001810
|
||||
| Drug Name |
ISIS 1570
|
||||
| Drug Type |
Antisense drug
|
||||
| Indication | Pouchitis [ICD10:K91.8] | Approved | [551871] | ||
| Company |
Isis Pharmaceuticals
|
||||
| Target and Pathway | |||||
| Target(s) | mRNA of Intercellularadhesion molecule-1 | Target Info | [549645] | ||
| KEGG Pathway | NF-kappa B signaling pathway | ||||
| Cell adhesion molecules (CAMs) | |||||
| Natural killer cell mediated cytotoxicity | |||||
| TNF signaling pathway | |||||
| Leukocyte transendothelial migration | |||||
| African trypanosomiasis | |||||
| Malaria | |||||
| Staphylococcus aureus infection | |||||
| Influenza A | |||||
| HTLV-I infection | |||||
| Epstein-Barr virus infection | |||||
| Rheumatoid arthritis | |||||
| Viral myocarditis | |||||
| WikiPathways | Type II interferon signaling (IFNG) | ||||
| IL1 and megakaryotyces in obesity | |||||
| Human Complement System | |||||
| Spinal Cord Injury | |||||
| Interleukin-11 Signaling Pathway | |||||
| RANKL/RANK Signaling Pathway | |||||
| Integrin cell surface interactions | |||||
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | |||||
| Folate Metabolism | |||||
| Vitamin B12 Metabolism | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
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