Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07ESC
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| Former ID |
DCL000699
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| Drug Name |
Apremilast
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| Synonyms |
Apremilast (USAN); CC-10004; N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide
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| Drug Type |
Small molecular drug
|
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| Company |
Celgene
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| Structure |
|
Download2D MOL |
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| Formula |
C22H24N2O7S
|
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| InChI |
InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
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| InChIKey |
IMOZEMNVLZVGJZ-QGZVFWFLSA-N
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| CAS Number |
CAS 608141-41-9
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| PubChem Compound ID | |||||
| PubChem Substance ID |
16663888, 28672022, 42703565, 50086920, 78553422, 96025543, 103594774, 104103394, 135195808, 135299279, 136946493, 140792549, 144115618, 152256090, 152258393, 160647230, 164045129, 164194075, 176253765, 178103944, 186014493, 187575333, 189561506, 198938842, 198994002, 218902332, 223380767, 223443866, 223593318, 224603101, 226643371, 247101845, 249492055, 249814467, 250163167, 251962967, 251970550, 252088578, 252160602, 252214744, 252438251, 252451837, 252553654
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| SuperDrug ATC ID |
L04AA32
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| Target and Pathway | |||||
| Target(s) | PDE4 | Target Info | Inhibitor | [537117] | |
| References | |||||
| Ref 537117 | Emerging drugs for psoriasis. Expert Opin Emerg Drugs. 2009 Mar;14(1):145-63. | ||||
| Ref 542394 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7372). | ||||
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