Drug Information
Drug General Information | |||||
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Drug ID |
D09LSX
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Former ID |
DNC006237
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Drug Name |
KU-0058948
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Drug Type |
Small molecular drug
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Indication | Ovarian cancer [ICD9: 183; ICD10:C56] | Approved | [533123] | ||
Structure |
Download2D MOL |
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Formula |
C21H21FN4O2
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Canonical SMILES |
C1CNCCN(C1)C(=O)C2=C(C=CC(=C2)CC3=NNC(=O)C4=CC=CC=C43)F
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InChI |
1S/C21H21FN4O2/c22-18-7-6-14(12-17(18)21(28)26-10-3-8-23-9-11-26)13-19-15-4-1-2-5-16(15)20(27)25-24-19/h1-2,4-7,12,23H,3,8-11,13H2,(H,25,27)
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InChIKey |
HGEPGGJUGUMFHT-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Poly [ADP-ribose] polymerase-1 | Target Info | Inhibitor | [530062] | |
KEGG Pathway | Base excision repair | ||||
NF-kappa B signaling pathway | |||||
PANTHER Pathway | FAS signaling pathway | ||||
Pathway Interaction Database | Integrin-linked kinase signaling | ||||
Caspase Cascade in Apoptosis | |||||
Notch-mediated HES/HEY network | |||||
Reactome | Dual Incision in GG-NER | ||||
References |
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