Drug Information
Drug General Information | |||||
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Drug ID |
D02CTS
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Former ID |
DCL001219
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Drug Name |
Ospemifene
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Drug Type |
Small molecular drug
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Company |
Shionogi; QuatRx
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Structure |
Download2D MOL |
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Formula |
C24H23ClO2
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InChI |
InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-
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InChIKey |
LUMKNAVTFCDUIE-VHXPQNKSSA-N
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CAS Number |
CAS 128607-22-7
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
SuperDrug ATC ID |
G03XC05
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Target and Pathway | |||||
Target(s) | Estrogen receptor | Target Info | Modulator | [551684] | |
Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
Signaling events mediated by HDAC Class II | |||||
Plasma membrane estrogen receptor signaling | |||||
LKB1 signaling events | |||||
Regulation of Telomerase | |||||
ATF-2 transcription factor network | |||||
AP-1 transcription factor network | |||||
FOXM1 transcription factor network | |||||
Validated nuclear estrogen receptor alpha network | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
FOXA1 transcription factor network | |||||
References | |||||
Ref 532651 | 2013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85-9. | ||||
Ref 542369 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7349). | ||||
Ref 551684 | Clinical pipeline report, company report or official report of Shionogi (2011). |
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