Drug General Information |
Drug ID |
D0OB0F
|
Former ID |
DCL000369
|
Drug Name |
Bosutinib
|
Synonyms |
SKI 606; SKI606; Bosutinib (USAN); PF-5208763; SKI-606; Xy]-3-quinolinecarbonitrile; 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile; 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile; 4-(2,4-dichloro-5-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propo; 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile; Bosutinib (BCR-ABL inhibitor 3rd gen)
|
Drug Type |
Small molecular drug
|
Therapeutic Class |
Anticancer Agents
|
Company |
Wyeth Research
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C26H29Cl2N5O3
|
InChI |
InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)
|
InChIKey |
UBPYILGKFZZVDX-UHFFFAOYSA-N
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CAS Number |
CAS 380843-75-4
|
PubChem Compound ID |
|
PubChem Substance ID |
8034215, 11061176, 14720373, 14885411, 17397405, 26676000, 26746630, 39301565, 53641516, 56459346, 57361290, 85246176, 92721109, 103220856, 113911152, 118844931, 124950167, 125011711, 125349351, 126627733, 126647930, 126666992, 126731247, 134339019, 134964339, 135246638, 135642791, 135684978, 135685144, 135685145, 135685164, 135697655, 136340225, 136368026, 136920303, 137127131, 139943916, 143495997, 144115749, 152041940, 152234943, 152258097, 152344342, 160646936, 162011701, 162170730, 162201602, 162256836, 163884826, 164041898
|
ChEBI ID |
ChEBI:39112
|
SuperDrug ATC ID |
L01XE14
|
Drug Resistance Mutation (DRM) |
Target and Pathway |
References |