Drug General Information
Drug ID
D0W2EK
Former ID
DAP001562
Drug Name
Ixabepilone
Synonyms
Azaepothilone B; BMS-247550; Ixempra (TN)
Drug Type
Small molecular drug
Indication Advanced breast cancer [ICD9: 174, 175; ICD10:C50] Approved [529282], [531351], [541906]
Company
Bristol-Myers Squibb
Structure
Download
2D MOL

3D MOL

Formula
C27H42N2O5S
InChI
InChI=1S/C27H42N2O5S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)29-23(31)13-21(30)26(5,6)25(33)17(3)24(15)32/h11,14-15,17,20-22,24,30,32H,8-10,12-13H2,1-7H3,(H,29,31)/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1
InChIKey
FABUFPQFXZVHFB-PVYNADRNSA-N
CAS Number
CAS 219989-84-1
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
L01DC04
Target and Pathway
Target(s) Tubulin Target Info Stablizer [531351]
References
Ref 5292822007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.
Ref 531351Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.
Ref 541906(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6824).
Ref 531351Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.

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