Drug Information

Drug General Information
Drug ID
D0LM4A
Former ID
DAP000265
Drug Name
Varenicline
Synonyms
CP 526555; Champix (TN); Chantix (TN); Varenicline (INN); 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine; 7,8,9,10-tetrahydro-6h-6,10-methanoazepino[4,5-g]quinoxaline
Drug Type
Small molecular drug
Indication Smoking cessation [ICD9: 292; ICD10:F17.2] Approved [528715], [540860]
Company
Pfizer Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C13H13N3
InChI
InChI=1S/C13H13N3/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1/h1-2,4-5,8-9,14H,3,6-7H2/t8-,9+
InChIKey
JQSHBVHOMNKWFT-DTORHVGOSA-N
CAS Number
CAS 249296-44-4
PubChem Compound ID
5310966
PubChem Substance ID
7978537, 11056173, 16411442, 39340702, 46505502, 57359304, 75856952, 117645007, 126616857, 126649068, 134337579, 135659813, 135724135, 137001274, 140812779, 160964599, 175265331, 177748982, 178102109, 196106108, 223736542, 226504643, 241376623, 246170038, 249738252, 252157510
SuperDrug ATC ID
N07BA03
Target and Pathway
Target(s) Nicotinic ACh receptor alpha 4/beta 2 Target Info Modulator [528715]
References
Ref 5287152006 drug approvals: finding the niche. Nat Rev Drug Discov. 2007 Feb;6(2):99-101.
Ref 540860(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5459).
Ref 5287152006 drug approvals: finding the niche. Nat Rev Drug Discov. 2007 Feb;6(2):99-101.

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