Drug General Information
Drug ID
D0N2EF
Former ID
DAP001490
Drug Name
Lipo-alprostadil
Drug Type
Small molecular drug
Indication Diabetic foot ulcer [ICD9: 707; ICD10:L88-L89] Approved [536297]
Company
Taisho Licensee Mitsubishi Pharma
Structure
Download
2D MOL

3D MOL

Formula
C20H34O5
Canonical SMILES
CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O
InChI
1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
InChIKey
GMVPRGQOIOIIMI-DWKJAMRDSA-N
CAS Number
CAS 745-65-3
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:15544
SuperDrug ATC ID
C01EA01
SuperDrug CAS ID
cas=000745653
Target and Pathway
Target(s) Prostaglandin E2receptor, EP2 subtype Target Info Agonist [536297]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
Renin secretion
Pathways in cancer
Reactome Prostanoid ligand receptors
G alpha (s) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Ovarian Infertility Genes
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536297Emerging drugs for diabetic foot ulcers. Expert Opin Emerg Drugs. 2006 Nov;11(4):709-24.
Ref 536297Emerging drugs for diabetic foot ulcers. Expert Opin Emerg Drugs. 2006 Nov;11(4):709-24.

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